Mufeed Jalil Ewadh
University of Babylon, IRAQ
Title: Correlation of Reduced Glutathione with Brest Cancer Using High Performance Liquid Chromatography
Biography
Biography: Mufeed Jalil Ewadh
Abstract
Breast cancer (BC) is a type of malignancy appeared in breast tissue, occurs in both premenopausal and also in postmenopausal women’s. Glutathione (GSH) is a tripeptide that is found intracellularly in high concentration, being the most abundant low molecular mass thiol .A total of 80 patient with (BC) divided in two groups, first group (n=40) women with breast cancer without chemotherapy, second group (n= 40 ) women with breast cancer with chemotherapy. The control group (n= 40) apparently healthy women’s matched with patient group. Women with (BC) have a significant lower serum level of (GSH) than those who are not diseased and even than those who received chemotherapy (pË‚ 0.05) So, this lead to a conclusion that; breast cancer women have low level of GSH and increased upon administration of chemotherapy. The objective of this study is to assess GSH status in women’s BC receiving chemotherapy treatment.