Manal H. Al Khanbashi
Higher College of Technology, Sultanate of Oman
Title: Evidences on physical activities effect on breast cancer: Epigenetics prospective
Biography
Biography: Manal H. Al Khanbashi
Abstract
Worldwide, breast cancer is the second leading cause of death in females exhibiting a significant global health burden. Piling evidences based on the reversibility nature of the epigenetics effects like physical activity and dietary habits may play a pivotal role in disease manifestation.
Among the most effective intervention that has an effect on cancer is the physical activity in which at moderate levels showed to reduce the risk of death from breast cancer and many other chronic diseases. Studies have showed high and low intensity supervised multimodal intervention exercises reduced cancer patients fatigues, muscular strength and improved patients’ wellbeing. Based on gene methylation expression data of breast cancer patients undergoing randomized clinical trial exercise revealed reduction in gene methylation of tumour suppressor genes in association with overall survival.
Herein, this study will give an overview on the predisposition of such exogenous epigenetic effects of physical activities on the potential reversibility and preventive possibilities of breast cancer.